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Catalog# Product Description |
ICP0435 PKB alpha (AKT1) is a member of the PKB family, which is responsive to cell activation. The anti-AKT1 antibody was raised with a peptide derived from the C-terminal sequence of human AKT1 and affinity purified with the same peptide as the affinity matrix. |
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Species
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Rabbit
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Formulation
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250 μg/mL in TBS, 50% glycerol, 0.01% NaN3
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Immunogen
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Human AKT1 C-terminal peptide KLH conjugates
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Purification
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Affinity purified with AKT1 peptide
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Specificity
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The antibody recognizes AKT1 in human and mouse.
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Applications
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ELISA (0.25 - 1.0 μg/mL); WB (0.25 - 1.0 μg/mL)
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Scientific Description
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Protein kinase B or AKT (PKB/Akt) is a serine/threonine kinase. In mammals three highly homologous members of AKT are PKB alpha (AKT1), PKB beta (AKT2) and PKB gamma (AKT3). This enzyme is involved in important cellular processes such as glucose metabolism, cell proliferation, apoptosis, transcription and cell migration.
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Storage & Stability
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Product is stable for several weeks at 4°C. For extended storage, store product at –20oC. Expiration date is one year from date of shipping if properly stored.
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Product Specific References
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1. Curr. Opin. Cell Biol. 1998. 10(2): 262-267. doi: 10.1038/10026
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