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Catalog# Product Description |
ICP0280 ING1 is a tumour suppressor. Affinity purified rabbit polyclonal anti-p33 ING1 is developed with the N-terminal peptide based on mouse p33 ING1, the identical sequence of human p33 ING1. |
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A: Cell expressed-flag p33 ING1, blot with Ab from other commercial source. B: Cell expressed p33 ING1, blot with Ab from other commercial source. C: Cell expressed-flag p33 ING1, blot with Ab ICP0280. D: Cell expressed p33 ING1, blot with Ab ICP0280.
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Species
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Rabbit
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Formulation
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250 μg/mL in TBS, 50% glycerol, 0.01% NaN3
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Immunogen
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Mouse p33 ING1 N-terminal peptide-KLH conjugates
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Purification
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The antibody was affinity purified with p33 ING C-terminal peptide on agarose.
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Specificity
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The antibody recognizes p33 ING1 of human and mouse. There are no cross reactions with other members of the ING family.
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Applications
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ELISA (0.5 μg/mL); WB (1 μg/mL); IFC (1:50)
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Scientific Description
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p33 (ING1) is a new growth inhibitor candidate for a tumour suppressor gene. p33 (ING1) cooperates with p53 and down-regulates cell growth by activating transcription from the p21/WAF1 promoter although there is no sequence similarity between p33 (ING1) and p53.
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Storage & Stability
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Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.
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Product Specific References
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1. Cancer Lett. 1999. 147: 157-162. doi:10.1016/SD3D4-3835(99)00288-8
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