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Catalog# Product Description |
IAN2010 This antibody was developed and affinity purified using a peptide based on human MEK1. This antibody was tested to be able to detect both human MEK1 and MEK2 using human cell lysates. |
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Representative western blot with anti-MEK1/2 (1:1000) using, from left to right, 10 μg, 20 μg and 40 μg of 293 cell lysate.
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Species
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Rabbit
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Formulation
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1000 μg/mL in TBS with 50% glycerol
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Immunogen
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MEK1 peptide (210-255 aa) KLH conjugates
Protein code: Q02750
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Purification
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Affinity specific affinity chromatography
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Specificity
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Recognizes both MEK1 and MEK 2 , human and mouse
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Applications
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ELISA (>1:2000); WB (>1:1000); IP (5 μg/mg protein)
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Scientific Description
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MEK1 is a member of the dual specificity protein kinase family that acts as a mitogen-activated protein kinase (MAPK) kinase. MEK1 lies upstream of MAPK/ERK and stimulates the enzymatic activity of MAPK/ERK upon a wide variety of extra- and intracellular signals. As an essential component of MAPK/ERK signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
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Storage & Stability
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Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.
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