Catalog#
Species
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ICP5012
Rabbit
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Formulation
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250 μg/mL in TBS, 50% glycerol, 0.01% NaN3
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Immunogen
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Human histone H4 C-terminal peptide KLH conjugates
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Purification
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The antibody was affinity purified with histone H4 peptide on agarose.
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Specificity
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The antibody recognizes histone H4 from human, rat, bovine, mouse and rabbit. It does not cross react with histone H1, H2 or H3.
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Applications
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ELISA (0.25 - 1.0 μg/mL); WB (0.25 - 1.0 μg/mL); IP
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Scientific Description
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Histone are the main proteins of chromatin, acting as spools around which DNA winds. Histones are also involved in gene regulation. One of the five histone proteins is called histone H4. It consists of a main globular domain and a long N-terminal tail. It is involved with the "beads on a string" structure of the nucleosome.
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Storage & Stability
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Product is stable for several weeks at 4°C. For extended storage, store product at –20oC. Expiration date is one year from date of shipping if properly stored.
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Product Specific References
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1. Stein, G. S. “Histones and other basic nuclear proteins”. 1989, CRC.
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